Oxidative stress and the etiology of male infertility
نویسندگان
چکیده
منابع مشابه
Oxidative stress & male infertility.
The male factor is considered a major contributory factor to infertility. Apart from the conventional causes for male infertility such as varicocoele, cryptorchidism, infections, obstructive lesions, cystic fibrosis, trauma, and tumours, a new and important cause has been identified: oxidative stress. Oxidative stress is a result of the imbalance between reactive oxygen species (ROS) and antiox...
متن کاملA Review: Role of oxidative stress in male infertility
Recent studies have shown that reactive oxygen species (ROS) have a very important role in the intracellular signaling process in physiological conditions. On the other hand, during the recent decade it has been indicated that ROS play a role in various types of male infertility and it is due to the overproduction of ROS or decrease in the antioxidant defense system in the reproductive system a...
متن کاملRole of oxidative stress and antioxidants in male infertility.
Oxygen toxicity is an inherent challenge to aerobic life, including spermatozoa, the cells responsible for propagation of the species. How this toxicity affects the spermatozoan in its interactions with the ovum is still unknown. An increase in oxidative damage to sperm membranes, proteins, and DNA is associated with alterations in signal transduction mechanisms that affect fertility. Recent ev...
متن کاملOxidative stress and sperm chromatin damage in male infertility.
Researchers studying the causes of male infertility have recently focused on the role played by reactive oxygen species (ROS)—a highly reactive oxidizing agent belonging to the class of free radicals. ROS are produced by a variety of semen components, and antioxidants in the seminal fluid keep their levels in check. Small amounts of ROS help spermatozoa acquire their necessary fertilizing capab...
متن کاملRelationship amongst teratozoospermia, seminal oxidative stress and male infertility
BACKGROUND Spermatozoa morphology is an important and complex characteristic of the fertilization capacity of male germ cells. Morphological abnormalities have been observed to be accompanied by reactive oxygen species (ROS) overproduction and further damage to spermatozoa, ultimately leading to infertility. Therefore, this study aimed to examine the relationship between seminal ROS production ...
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ژورنال
عنوان ژورنال: Journal of Assisted Reproduction and Genetics
سال: 2016
ISSN: 1058-0468,1573-7330
DOI: 10.1007/s10815-016-0791-4